Dolutegravir pharmacokinetics in pregnant and postpartum women living with HIV
نویسندگان
چکیده
منابع مشابه
Etravirine Pharmacokinetics in HIV-Infected Pregnant Women
BACKGROUND The study goal was to describe etravirine pharmacokinetics during pregnancy and postpartum in HIV-infected women. METHODS IMPAACT P1026s and PANNA are on-going, non-randomized, open-label, parallel-group, multi-center phase-IV prospective studies in HIV-infected pregnant women. Intensive steady-state 12-h pharmacokinetic profiles were performed from 2nd trimester through postpartum...
متن کاملLifestyle of Women Living with HIV (Case Study: Women Living with HIV in the Positive Club of Kerman)
Background and Objectives: Although everyone needs to adopt a healthy lifestyle, it is absolutely important for people living with chronic diseases like HIV/AIDS to lead a positive lifestyle because these people are more vulnerable than others. Considering this fact, the present study was conducted to investigates the lifestyle of women living with HIV/AIDS in Kerman. Methods:The Health-prom...
متن کاملMaraviroc Pharmacokinetics in HIV-1-Infected Pregnant Women.
OBJECTIVE To describe the pharmacokinetics of maraviroc in human immunodeficiency virus (HIV)-infected women during pregnancy and post partum. METHODS HIV-infected pregnant women receiving maraviroc as part of clinical care had intensive steady-state 12-hour pharmacokinetic profiles performed during the third trimester and ≥2 weeks after delivery. Cord blood samples and matching maternal bloo...
متن کاملSingle and multiple dose pharmacokinetics of dolutegravir in the genital tract of HIV-negative women.
BACKGROUND Antiretrovirals that achieve adequate concentrations in anatomical sites of transmission are of interest for HIV prevention. A Phase I open-label pharmacokinetic (PK) study was performed to describe first dose (PK1) and steady-state (PK2) PKs of the integrase inhibitor dolutegravir (DTG) in blood plasma (BP), cervicovaginal fluid (CVF), cervical tissue (CT) and vaginal tissue (VT) in...
متن کاملHIV and reproductive healthcare in pregnant and postpartum HIV-infected women: adapting successful strategies.
Linkage and retention in care for many HIV-infected women in the postpartum period is suboptimal, which compromises long-term virologic suppression and the HIV Care Continuum. Efforts are needed to improve individual outcomes by addressing transitions in care. We summarize some successful strategies to engage and retain HIV-infected women in care during the postpartum period.
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ژورنال
عنوان ژورنال: AIDS
سال: 2018
ISSN: 0269-9370
DOI: 10.1097/qad.0000000000001755